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Application Notes: 2-Amino-5-(trifluoromethyl)-4-thiazolecarboxylic Acid is a derivative of 2-Aamino-4-thiazolecarboxylic Acid Ethyl Ester (E678465), a chemical reagent used in the preparation fo SAR thiazolamino arylaminopyrimidines as anaplastic lymphoma kinase inhibitors. As well as in the synthesis of 4-bicyclick piperadine derivatives as potent stearoyl-CoA desaturase (SCD1) inhibitors in the treatment of cancer. /// References: Liu, Z. et al.: Eur. J. Med. Chem., 86, 438 (2014)| Noto, A. et al.: Cell Death Disease, 4, e947 (2013)|