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Category: Amines, Heterocycles, Miscellaneous Reagents, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: (1alpha,5alpha,6alpha)-6-Amino-3-azabicyclo[3.1.0]hexane-3-carboxylic Acid 1,1-Dimethylethyl Ester, is an intermediate in the preparation of a novel series of Histone Deacetylase (HDAC) Inhibitors, demonstrating class I selectivity and good oral bioavailability. It can also be used in the synthesis of Alatrofloxacin Mesylate (A511400). /// References: Moffat, D., et al.: J. Med Chem., 53, 8663 (2010)| Gladue, R., et al.: Antimicrob. Agent Chemother., 34, 1056 (1990)| Bailly, S., et al.: Clin. Exp. Immunol., 85, 331 (1991)|