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Category: Amines, Chiral Reagents, Isotope Labelled Compounds, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: (2R,4R,5R,7S)-Aliskiren-d6 Fumarate (2:1) is the labeled anaogue of (2R,4R,5R,7S)-Aliskiren Fumarate (2:1) (A536025), an isomer of Aliskiren Hemifumarate (A536001), an orally active, synthetic nonpeptide renin inhibitor. Antihypertensive. /// References: Lefevre, G., et al.: J. Immunoassay, 21, 65 (2000)| Allikments, K., et al.: Curr. Opin. Invest. Drugs, 3, 1479 (2002)| Wood| J.M., et al.: Biochem. Biophys. Res. Commun., 308, 698 (2003)| Grandman, A.H., et al.: Circulation, 111, 1012 (2005)