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Category: Isotope Labelled Compounds, Amines, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Light Grey Solid /// Application Notes: (R,S,R)-2-Acetyl-4-(1,2,3,4-tetrahydroxybutyl)-imidazole-13C6 is the isotope labelled analog of (R,S,R)-2-Acetyl-4-(1,2,3,4-tetrahydroxybutyl)-imidazole (A188490). (R,S,R)-2-Acetyl-4-(1,2,3,4-tetrahydroxybutyl)-imidazole (THI) inhibits sphinogosine-1-phosphate (S1P) lyase for treatment of autoimmune disorders. /// References: Zhang, H., et al.: Tetrahedron, 69, 4041 (2013)| Bagdanoff, J.T., et al.: J. Med. Chem., 53, 8650 (2010)| Bagdanoff, J.T., et al.: J. Med. Chem., 52, 3941 (2009)