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Beschreibung

Category: Carbohydrates and Derivatives, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: White to Light Beige Solid /// Application Notes: N-Acetyl-9-(acetylamino)-9-deoxyneuraminic Acid is a ynthetic sialic acid analogue and the 9-acetamido derivative of N-Acetylneuraminic Acid (A187000). N-Acetyl-9-(acetylamino)-9-deoxyneuraminic Acid can be used by influenza C virus as a receptor determinant for attachment to cells. Modified erythrocytes containing N-Acetyl-9-(acetylamino)-9-deoxyneuraminic Acid were agglutinated by influenza C virus to the same titer as the 9-O-acetyl analogue but was shown to be resistant to cleavage by the viral acetylesterase. /// References: Herrler, G. et al.: Acta Histochem. Supp., 40, 39 (1990)| Herrler, G. et al.: Biochem. Biophys. Res. Comm., 216, 821 (1995)| Herrler, G. et al.: J. Biol. Chem., 267, 12501 (1992)|