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Beschreibung

Category: Amines, Apoptosis, Aromatics, Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals, Sulfur and Selenium Compounds /// Appearance: Yellow Solid /// Application Notes: ABT 199 is a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets. It's practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer. /// References: Davids, M. & Letai, A.: Cancer Cell, 23, 139 (2013)| Souers, A.,et al.: Nat. Med., 19, 202 (2013)| Vaillant, F., et al.: Cancer Cell, 24, 120 (2013)| Vogler, M., et al.: Brit. J. Haematol., 163, 139 (2013)|