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Beschreibung

The BioTracker DCM-Bgal live cell dye is a ratiometric near-infrared (NIR) dye for the real-time fluorescent quantification of beta-galatosidase (ß-gal) enzyme activity in vitro, in vivo and in situ.ß-galactosidase is an important marker for cell senescence and primary ovarian cancers. BioTracker DCM-Bgal live cell dye has light-up ratiometric NIR fluorescence withlarge Stokes shift, high photostability than commercial ICG, and pH independency under the physiological range, allowing for the real-timeevaluation of beta-gal activity. DCM-betagal displays higher affinity for beta-galthan commercial X-gal and much faster response to beta-gal thanthe previously reported FDG.Spectral Properties:NIR fluorescence images obtained from 605 to 725 nm, lambdaex = 560 nmResearch Categories:Apoptosis & CancerCell ImagingOncology