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Beschreibung

Cytokine receptors constitute an integral part of the cytokine biology. Like cytokines, cytokine receptors are involved in normal physiological and pathological processes of almost all disease states. Soluble cytokine receptors naturally arise from genes encoding membrane-bound receptors or are direct derivatives of the receptors themselves. The discovery that soluble cytokine receptors are involved in regulating excessive inflammatory responses and modulating immune events has stimulated significant research interest in their potential role as immunotherapeutic agents. Many of these soluble cytokine receptors have the ability to inhibit the binding and biological activity of their cytokine ligands, making them very specific cytokine antagonists. The MILLIPLEX(R) Mouse Soluble Cytokine Receptor Panel contains 13 metastasis biomarkers that have also been identified in a variety of therapeutic areas. Coupled with the Luminex(R) xMAP(R) platform in bead format, this panel enables researchers to focus on discovery with the advantage of simultaneous quantitative multiplex detection leading to speed and sensitivity. Panel Type: Cytokines/Chemokines