Artikelnr.
SAF-616453-2MG
CAS-Nummer
[356559-13-2]
Einheit
1 x 2 mg
Molekularformel
C20H22ClN3O2
Molekulargewicht
335,40 (anhydrous free base basis)
Transportdaten
No Dangerous Good /not restricted
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Beschreibung
A cell-permeable imidazolyl-pyridine compound that acts as a potent, ATP-competitive, reversible, and selective inhibitor of activin receptor-like kinase 4 (IC50 = 129 nM), 5 ( IC50 = 47 nM), and 7. It inhibits p38 MAPKalpha only at much higher concentrations (IC50 = 10.6 µ,M) and has little effect against ALK1/2/3/6 as well as a panel of 26 other kinases.
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