Artikelnr.
SAF-539749-2MG
Einheit
1 x 2 mg
Transportdaten
No Dangerous Good
A cell-permeable, selective, reversible, and non-competitive allosteric inhibitor of PTP1B (IC50 = 4 µ,M and 8 µ,M for PTP1B403 and PTP1B298, respectively). Binds to a novel site away from the catalytic pocket and inhibits PTP1B activity by preventing closure of the WPD loop.

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