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Beschreibung

A cell-permeable inhibtor of protein kinase C (IC50 = 20-50 µ,M). Activates Ca2+-activated K+ channels in amphibian myelinated nerve fibers at micromolar concentrations. An inhibitor of myo-inositol uptake. Also inhibits L-type Ca2+ channel activity. A potent inhibitor of 5'-iodothyronine deiodinase. Antagonist of prostaglandin F2alpha receptors linked to phospholipase C in astrocytes.