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Beschreibung

A cell-permeable methoxylated analog of Resveratrol (Cat. No. 554325) that displays antioxidant, antiproliferative, and hypoglycemic properties. Moderately inhibits COX-1 and -2 activities (IC50 = 19.8 µ,M and 83.9 µ,M) respectively, induces apoptosis in HL60 cells (IC50 = 70 µ,M), prevents DMBA-induced preneoplastic lesions (ED50 = 4.8 µ,M) and decreases plasma glucose level in streptozotocin-induced diabetic rats comparable to that of Metformin., A cell-permeable methoxylated analog of Resveratrol (Cat. No. 554325) that displays antioxidant, anti-proliferative, and hypoglycemic properties. Appears to be a better free radical scavenger than Trolox (Cat. No. 64847). Moderately inhibits COX-1 & COX-2 activities (IC50 = 19.8 µ,M & 83.9 µ,M, respectively) and induces apoptosis in HL60 cells (IC50 = 70 µ,M). Also prevents DMBA-induced pre-neoplastic lesions (ED50 = 4.8 µ,M). Reported to decrease plasma glucose levels in streptozotocin-induced diabetic rats comparable to that of Metformin.