Artikelnr.
SAF-517301-10MG
Einheit
1 x 10 mg
Molekularformel
C23H18ClNO4
Molekulargewicht
407,85
Transportdaten
No Dangerous Good
A cell-permeable cinnamoyl compound that reversibly inhibits P-gp (P-glycoprotein) efflux function and reverses the MDR (multidrug resistance) phenotype with no noticeable effect on P-gp expression. Shown to significantly enhance Paclitaxel- (Cat. No. 580555) and Vincristine- (Cat. No. 677181) induced cytotoxicity as well as apoptosis in P-gp expressing KBV20C cells.

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