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Beschreibung

A potent and competitive antagonist for AMPA/kainate receptors (Ki = 0.6 - 2.11 µ,M for GluA1-4 and Ki = 1.3-5.3 µ,M for different subtypes of Kainate receptors) and a negative allosteric modulator at NMDA receptor glycine binding site. Widely used for assessing the functional roles of neurotransmission mediated by glutamate receptors in both normal and abnormal brain functions., A potent and competitive antagonist for AMPA/kainate receptors (Ki = 0.6 - 2.11 µ,M for GluA1-4 and Ki = 1.3-5.3 µ,M for different subtypes of Kainate receptors) and a negative allosteric modulator at NMDA receptor glycine binding site. Widely used for assessing the functional roles of neurotransmission mediated by glutamate receptors in both normal and abnormal brain functions.Please note that the molecular weight for this compound is batch-specific due to variable water content.