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Beschreibung

A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM). Inhibits protein kinase A (Ki = 21 µ,M)and protein kinase C (Ki = 42 µ,M) at much higher concentrations., A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM). Inhibits protein kinase A (Ki = 21 µ,M) and protein kinase C (Ki = 42 µ,M) at much higher concentrations.

Strukturformel

1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4 -diazepine, Hydrochloride

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