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sFRP-1 Inhibitor - CAS 915754-88-0 - Calbiochem The sFRP-1 Inhibitor, also referenced under CAS 915754-88-0, controls the biological activity of sFRP-1. This small molecule/inhibitor is primarily used for Activators/Inducers applications.

Artikelnr.

SAF-344300-5MG

CAS-Nummer

[915754-88-0]

Einheit

1 x 5 mg

Molekularformel

C19H26N2O4S2

Molekulargewicht

410,55

Transportdaten

No Dangerous Good

Preis auf Anfrage

Beschreibung

A diphenylsulfone-sulfonamide compound that counteracts the antagonizing effect of SARP-2/sFRP-1 (secreted frizzled related protein-1) against Wnt-3/frizzled interaction and Wnt-3/frizzled-stimulated cellular functions (EC50 = 1.27 microM in a U2OS-based reporter assay) with a reported aqueous solubility of 26 microg/ml at pH 7.4 and in vitro half-lives of 12 and 26.7 min using rat and human microsomes, respectively.

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