Artikelnr.
SAF-124029-2MG
Einheit
1 x 2 mg
Molekularformel
C39H39N7O2 · 3HCl
Molekulargewicht
747,16
Transportdaten
No Dangerous Good
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Beschreibung
A cell-permeable Akti-1/2- (Cat. No. 124018) derived allosteric inhibitor pair (1:1 regioisomeric mixture) with much improved aqueous solubility (10 mg/ml in a pH 7.4 saline) and Akt2 selectivity (IC50 = 805 nM for Akt2, >10 µ,M for Akt1/3, and >50 µ,M for PKA/PKC/SGK). The inhibition is PH domain-dependent and non-competitive with ATP., A cell-permeable Akti-1/2- (Cat. No. 124018) derived allosteric inhibitor pair (1:1 regioisomeric mixture) with much improved aqueous solubility (10 mg/ml in a pH 7.4 saline) and Akt2 selectivity (IC50 = 805 nM for Akt2, >10 µ,M for Akt1/3, and >50 µ,M for PKA/PKC/SGK). The inhibition is PH domain-dependent and non-competitive with ATP.
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