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Category: Intermediates, Steroids /// Application Notes: Zymosterol is an sterol intermediate in the biosynthesis of cholesterol (C432501). Cholesterol is a major component of all biological membranes, ~25% of total brain lipid is Cholesterol. Zymosterol was also found to be located in the plasma membrane of cultured human fibroblasts via labeling studies. /// References: Roland, E.D., et al.: J. Am. Chem. Soc., 111, 278 (1989)| Echevarria, F., et al.: J. Biol. Chem., 265, 8484 (1990)| Baranovskii, A.V., et al.: Russian. J. Bioorg. Chem., 28, 250 (2002)| Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934)|