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Beschreibung

Category: Aromatics, Isotope Labelled Compounds, Neurochemicals, Pharmaceuticals, Intermediates and Fine Chemicals, Sulfur and Selenium Compounds /// Appearance: Off-White to Pale Yellow Solid /// Application Notes: Zonisamide-13C2-15N is the labeled analogue of Zonisamide (Z700000), a sulfonamide antiseizure agent, blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potential therapeutic use as an antiepileptic drug. Anticonvulsant. /// References: Masuda, Y., et al.: Arzneim.-Forsch., 30, 477 (1980)| Hammond, E.J., et al.: Gen. Pharmacol., 18, 303 (1987)| Schmidt, D., et al.: Epilepsy Res., 15, 67 (1993)| Sorkin, E.M., et al.: Drugs, 45, 760 (1993)