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Category: Miscellaneous Reagents /// Appearance: Clear Colourless Oil /// Application Notes: Trimethyl Orthoformate is a reagent in the synthesis of CDK2/Cyclin A as antitumor agents derived from 3-aminopyrazole molecules. Also used in the preparation of PLD1/PLD2 selective inhibitors that decrease invasive migration of glioblastoma cells often associated with tumor progression. /// References: Pevarello, P. et al.: J. Med. Chem., 48, 2944 (2005)| O'Reilly, M. et al.: J. Med. Chem., 56, 2695 (2013)|