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Beschreibung

Category: Miscellaneous Reagents /// Appearance: Clear Colorless Oil /// Application Notes: 2,2,2-Trichloroethyl Chloroformate is a general reagent for the demethylation of tertiary methylamines. It is used as a reagent in the synthesis of a series of piperazine ureas as fatty acid amide hydrolase inhibitors and analgesics. Also used as a reagent in the synthesis of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists. /// References: Montzka, T.A., et al.: Tetrahedron Lett., 15, 1325 (1974)| Kono, M., et al.: Bioorg. Med. Chem., 22, 1468 (2014)| Gillespie, P., et al.: Bioorg. Med. Chem. Lett., 24, 949 (2014)