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Appearance: Pale Orange Solid /// Application Notes: 5,6,7,8-Tetrahydro-1-naphthalenol was used as a reagent in the synthesis of phosphonamidate and phosphonodiamidate prodrugs of adefovir and tenofovir which are used in the treatment of HIV infections. Also used in the synthesis of tetrahydronaphthalene-1-ol derivatives which were found to be promising potent antitumor agents. /// References: Pertusati, F., et al.: Eur. J. Med. Chem., 78, 259 (2014)| Dong, Y., et al.: Bioorg. Med. Chem. Lett., 19, 6289 (2009)|