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Beschreibung

Category: Aromatics, Chiral Reagents, Drug Analogues, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: White Solid /// Application Notes: Terconazole belongs to a new chemical class of antifungal agents, the triazoles. Terconazole has a far greater selectively for yeast cytochrome P-450 than for mammalian microsomal cytochrome P-450 and is used as topical treatment of mycotic vaginitis. Terconazole may also be used in vitro as a potent antifungal agent to prevent the morphogenetic transformation of yeast into (pseudo-)mycelium form of Candida albicans. /// References: Cauwenbergh, G., Vanden Bossch H.: J. Reprod. Med., 34, 588 (1989)| Del Palacio-Hernanz, A., et. al.: Chemioterapia, 3, 192 (1984)| Van Cutsem, J., et. al.: Chemotherapy, 29, 322 (1983)|