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Category: Aliphatics, Amines, Pharmaceuticals, Intermediates and Fine Chemicals, Isotope Labelled Compounds /// Application Notes: Synaptamide-d4 is labelled Synaptamide (S910000) which is an endocannabinoid-like derivative of docosahexaenoic acid with cannabinoid-independent function. It has potent synaptogenic activity and structural similarity to anandamide. Synaptamide (S910000) is subjected to hydrolysis by fatty acid amide hydrolase, and can be oxygenated to bioactive metabolites. /// References: Kim, H., et al.: Prostaglandins Leukot Essent Fatty Acids, 88, 121 (2013)| Burstein, S., et al.: Bioorg. Med. Chem., 16, 9644 (2008)| Fu, J., et al.: J. Biol. Chem., 282, 1518 (2007)