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Beschreibung

Category: Chiral Reagents, Metabolites and Impurities, Pharmaceuticals, Intermediates and Fine Chemicals, Sulfur and Selenium Compounds /// Appearance: Yellow Orange Solid /// Application Notes: (R)-Sulindac is the R-epimer metabolite of Sulinac (S699215). (S)-Sulindac increases the activity of the P 450 system better than (R)-Sulindac, but both epimers increase primarily the enzymes that oxidize (R)-Sulindac. /// References: Duggan, D., et al.: J. Pharmacol. Exp. Ther., 1977, 201, 8 (1977), Hamman, M., et al.: Biochem. Pharmacol., 60, 7 (2000), Grimaud, R., et al.: J. Biol. Chem., 276, 48915 (2001)