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Beschreibung

Category: Amines, Aromatics, Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Pale Yellow Solid /// Application Notes: SCH772984 is a novel and selective inhibitor of ERK1/2 that displays behaviors of both type I and type II kinase inhibitors and has nanomolar cellular potency in tumor cells with mutations in BRAF, NRA5, or KRAS and induces tumor regressions in xenograft models. /// References: Morris, E. J., et. al.: Cancer Discovery, 3, 742 (2013)