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Category: Heterocycles, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: (4-Pyridyl)acetone is a reactant in the synthesis of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. Cardiotonic. /// References: Singh, B.: Heterocycles, 23, 1479 (1985)| Alousi, A.A., et al.: J. Cardiovasc Pharmacol., 5, 792 (1983)| Maskin, C.S., et al.: Circulation, 67, 1065 (1983)| Sinoway, L.S., et al.: J. Am. Coll. Cardiol., 2, 327 (1983)| Baim, D.S., et al.: N. Engl. J. Med., 309, 748 (1983)