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Beschreibung

Category: Amines, Heterocycles, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Brownish Yellow Solid /// Application Notes: 2,4-Pyridinediamine was studies for its interaction with cholinesterase inhibitors, neostigmine (N390010) and edrophonium (E336000) as a combined treatment for the restoration of muscle contraction. Experiments have shown the doses of neostigmine and edrophonium could be halved when they were combined with a small small amount of 2,4-pyridinediamine without apparent loss of antagonistic potency. /// References: Requena, J., et al.: J. Gen. Physiol., 85, 789 (1985)| Biessels, P.T.M., et al.: Euro. J. Pharmacol., 106, 319 (1984)| Den, H., et al.: Euro. J. Pharmacol., 94, 353 (1983)| Biessels, P.T.M., et al.: Arch. Int. Pharmacodyn. Ther., 293, 228 (1988)|