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Category: Nucleotides, Bases and Related Reagents, Pharmaceuticals, Intermediates and Fine Chemicals, Protein Kinase Inhibitors and Activators /// Appearance: White Solid /// Application Notes: Puromycin is an aminonucleoside antibitotic. Puromycin acts as a protein synthesis inhibitor which interferes with translation by inhibiting ribosome functions. Puromycin is also a reversible inhibitor of dipeptidyl-peptidase II (serine peptidase) and cytosol alanyl aminopeptidase. /// References: Pestka, S. et al.: Ann. Rev. Micromiol., 8, 1559 (1997)| Dando, P.M. et al.: Biomed. Health Res., 13, 88 (1997)| McDonald, J.K. et al.: J. Biol. Chem., 243, 2028 (1968)|