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Beschreibung

Category: Amines, Aromatics, Heterocycles, Protein Kinase Inhibitors and Activators, Pharmaceuticals, Intermediates and Fine Chemicals, Sulfur and Selenium Compounds /// Application Notes: PKR Inhibitor is a drug which acts as a selective inhibitor of the enzyme double-stranded RNA-dependent protein kinase (PKR). It has been shown to effectively inhibit PKR function in vivo and has neuroprotective and nootropic effects in animal studies. /// References: Jammi, N., et al.: Biochem. Biophys. Res. Commun., 308, 50 (2003)| Ingrand, S., et al.: Neurosci. Lett., 409, 192 (2006)| Chen, H., et al.: Eur. J. Neurosci., 28, 2003 (2008)| Couturier, J., et al.: J. Biol. Chem., 285, 1272 (2010)