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Category: Aromatics, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: Labelled Pamoic Acid. Agonist of the orphan G protein-coupled receptor GPR35: a potent activator of extracellular signal-regulated kinase and beta-arrestin2 with antinociceptive activity. Used as an inhibitor in the real-time fluorescence enzymatic characterization study of specialized human DNA polymerases. Enzyme replacement therapy in pancreatic enzyme deficiency. /// References: Fonge H., et al.: Bioconjugate Chem., 18, 1924 (2007), Mayr, G.W., et al.: J. Biol. Chem., 282, 35424 (2007)| Zhao, P. et al.: Mol. Pharmacol., 78, 560 (2010)| Dorjsujen, D. et al.: Nuc. Acids Res., 37, e128 (2009)|