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Beschreibung

Category: Carbohydrates and Derivatives, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates and Fine Chemicals, Steroids /// Appearance: White Solid /// Application Notes: Labelled Ouabain (O714500). A cardiac glycoside that inhibits Na(+)/K(+) ATPase. It regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1. /// References: Padilha, A.S. et al.: Clin. Exp. Pharmacol. Physiol., 35, 801 (2008)| Blaustein, M.P. et al.: Clin. Exp. Hypertens. 20, 691 (1998)| van Huysse, J.W. et al.: Clin. Exp. Hypertens. 20, 657 (1998)|