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Category: Heterocycles, Nucleotides, Bases and Related Reagents, Isotope Labelled Compounds, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: White Solid /// Application Notes: beta-Nicotinamide Adenine Dinucleotide-13C5 Ammonium Salt is labelled beta-Nicotinamide Adenine Dinucleotide Ammonium Salt. beta-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. beta-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins. /// References: Dudev, T. et al.: J. Am. Chem. Soc., 132, 16533 (2010)| Kerbey, A. et al.: Biochem. J., 154, 327 (1976)| Lahiri, S.D. et al.: ACS Chem. Biol., 7, 571 (2012)|