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Category: Aromatics, Heterocycles, Isotope Labelled Compounds, Metabolites and Impurities, Nicotine Derivatives, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: N-Methyl-gamma-oxo-3-pyridinebutanamide-d3 is the isotope labelled analog of N-Methyl-gamma-oxo-3-pyridinebutanamide (M325855), a metabolite of Cotinine (C725004) which is a major metabolite of nicotine in humans. Also carcinogenic. /// References: Morselli, P.L, et al.: J. Med. Chem., 10, 1033 (1967)| Murphy, S.E. et. al.: Chem. Res. Toxicol. 12, 639 (1999)| Sugasawa, S., et al.: Pharma. Bull., et al.: 2, 39 (1954)| Thompson, J.A., et al.: J. Chromatog., 231, 53 (1982)| Seeman, J.I., et al.: J. Org. Chem., 51, 1548 (1986)