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Category: Isotope Labeled Compounds, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: 5-[3-(Methylamino)propyl]-5H-dibenz[b,f]azepine, is the labeled analgue of (3-Methylaminopropyl)-5H-dibenz[b,f]azepine (M265075), which is a tricyclic compound related to the antidepressive drug Imipramine (I465980), having capacity to inhibit the uptake of 5-hydoxy tryptamine (5-HT) by human platelets in vitro. It is also an impurity of Desipramine (D290050). /// References: Checkley, S.A, et al.: Br. J. Psychiatry, 138. 248 (1981), Zhu, M.Y., et al.: J. Neurochem., 70, 1547 (1998), Okugawa, G., et al.: J. Neuroindocrinol., 11, 887 (1999), Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003),| Todrick, A., et al.: J. Pharm. Pharmacol., 21, 751 (1969)|