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Beschreibung

Category: Amines, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Off-White Low Melting Solid /// Application Notes: Intermedine is an unsaturated monoester pyrrolizidine alkaloid that is extracted from the seeds of Amsinckia intermedia, a tarweed that causes enzootic hepatic cirrhosis in horses and hard liver disease in cattle. Intermedine is also a diastereomer of Lycopsamine (L487525), a pyrrolizidine alkaloid that is found in honey and in comfrey (a topical anti-inflammatory agent used to treat patients with arthritis and gout). /// References: Culvenor, C., et al.: J. Agr. Food Chem., 29 958 (1981)| Janes, D., et al.: Nat. Prod. Comm., 7, 861 (2012)| Li, Y. & Stermitz, F.: J. Nat. Prod., 51, 1289 (1988)| McCulloch, E.: Am. Vet. Med. Assoc., 96, 5 (1940)| Pawar, R., et al.: J. Sep. Sci., 33, 200 (2010)