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Category: Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates and Fine Chemicals, Sulfur and Selenium Compounds /// Application Notes: (1R,3S,5S)-3-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8,8-dimethyl-d3-8-azabicyclo[3.2.1]oct-6-en-8-ium Bromide is the labeled analogue of (1R,3S,5S)-3-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8,8-dimethyl-8-azabicyclo[3.2.1]oct-6-en-8-ium Bromide (H941715), an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator. /// References: Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994)| Donohue, J. F., et al.: Chest, 122, 47 (2002)| Profita, M., et al.: Allergy, 60, 1361 (2005)| Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006)|