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Category: Chiral Reagents, Heterocycles, Isotope Labelled Compounds, Metabolites and Impurities, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: Hexanoyl Docetaxel Metabolites M1 and M3-d6 is the isotope labelled analog of Hexanoyl Docetaxel Metabolites M1 and M3 (H294465), metabolites of Docetaxel (D494420) which is a semisynthetic derivative of Paclitaxel(P132500) and an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. Also an antineoplastic. /// References: Ringel, I., et al.: J. Natl. Cancer Inst., 83, 288 (1991)| Extra, J.-M., et al.: Cancer Res., 53, 1037 (1993)