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Category: Chiral Reagents, Fluorescent Labels and Indicators, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Orange Solid /// Application Notes: Flutax 1 is a fluorescent taxol derivative that binds to the taxol microtubule binding site with high affinity (Ka ~ 107M-1). Flutax 1 is useful for direct imaging of the microtubule cytoskeleton. Excitation maximum ~ 495 nm, emission maximum ~ 520 nm. /// References: Evangelio, J.A., et al.: Cell Motil., Cytoskeleton, 39, 73 (1995), Souto, A.A., et al.: Angew. Chem. Int. Ed. Engl., 34, 2710 (1995), Abal., M., et al.: Cell Motil. Cytoskeleton, 49, 1 (2001), Diaz, J.F., et al.: J. Biol. Chem., 275, 26265, 2001, XXX