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Category: Amines, Aromatics, Miscellaneous Reagents /// Appearance: Brown Solid /// Application Notes: Ethyl 5-amino-1-benzofuran-2-carboxylate is used as an synthetic intermediate in the preparation of indolebutylpiperazines, a class of dual 5-HT1A receptor agonists and serotonin reuptake inhibitors. Ethyl 5-amino-1-benzofuran-2-carboxylate was also used as a potential radiolabelled analog for melanoma imaging and targeted radiotherapy. /// References: Chezal, J.M., et al.: J. Medn. Chem., 51, 3133 (2008)| Heinrich, T., et al.: J. Medn. Chem., 47, 4684 (2004)|