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Category: Chiral Reagents, Heterocycles /// Application Notes: (-)-Dimethyl 2,3-O-isopropylidene-L-tartrate is used as a reagent to synthesize (+)-Migrastatin, a natural macrolide compound produced by Streptomyces 1 and 2 that acts as a tumour migration cell inhibitor. (-)-Dimethyl 2,3-O-isopropylidene-L-tartrate is also a derivative of Tartaric acid (L-isomer: T007630 and D-isomer: T007625), a compound that is used as a chiral complexing agent in synthetic chemistry. /// References: Chen, L., et al.: Nature, 464, 1062 (2010)| Gaul, C., et al.: J. Am. Chem. Soc., 125, 6042 (2003)| Heldin, E., et al.: Chromatographia, 32, 407 (1991)