Zurück zu Ihrem Suchergebnis

Beschreibung

Category: Amines, Heterocycles, Hydantoins and Derivatives, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: White Solid /// Application Notes: 3-Piperazinylmethyl-5,5-dimethylhydantoin Dihydrochloride, is a derivative of 5,5-Dimethylhydantoin (D473300). 3-Piperazinylmethyl-5,5-dimethylhydantoin is also part of a group of small molecules that have the ability to reversibly inhibit Protein Arginine Deiminase (PAD4), which can potentially be used to treat inflammatory bowel disease and cancer. /// References: Chumanevich, A., et al.: Am. J. Physiol-Endoc. M., 300, G929 (2011)| Wang, Y., et al.: J. Biol. Chem., 287, 25941 (2012)| Wei, L., et al.: J. Med. Chem., 56, 1715 (2013)