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Beschreibung

Appearance: Off-White Low Melting Solid /// Application Notes: 2,4-Dimethylbenzenesulfonyl Chloride is used as a reagent in the synthesis of dimethyl benzimidazolones as potent and selective inhibitors of BRPF1 bromodomain. 2,4-Dimethylbenzenesulfonyl Chloride is also used as a reagent in the synthesis of quinazoline analogs as glucocerebrosidase inhibitors with chaperone activity for the treatment of Gaucher disease. /// References: Demont, E.H., et al.: ACS Med. Chem. Lett., 5, 1190 (2014)| Marugan, J.J., et al.: J. Med. Chem., 54, 1033 (2011)