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Beschreibung

Category: Amino Acids and Derivatives, Chiral Reagents, Inhibitors, Isotope Labelled Compounds /// Application Notes: Labelled 2,4-Diaminobutyric Acid. 2,4-Diaminobutyric Acid is a pharmacological tool and potential chiral building block. 2,4-Diaminobutyric Acid is also used as an internal standard for amino acid analysis. 2,4-Diaminobutyric Acid is also found to inhibit GABA transaminase, thus producing an elevation of GABA level, and to have an antitumor activity in vitro and in vivo against mouse fibrosarcoma cells. /// References: Riordan, J.F. et al.: Methods Enzymol., 47, 31 (1977)| Beart, P.M. et al.: Neurscience Lett., 5, 193 (1977)| Ronquist, G. et al.: J. Cancer Res. Clin. Oncol., 96, 259 (1980)| Solladie-Cavallo, A. et al.: Tetrahedron Lett., 30, 6011 (1989)|