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Beschreibung

Category: Amines, Aromatics, Metabolites and Impurities, Pharmaceuticals, Intermediates and Fine Chemicals, Sulfur and Selenium Compounds /// Application Notes: Deoxysotalol is the metabolite of Sotalol (S677300), a potent alpha-adrenergic receptor antagonist and A class III antiarrythmic. Several studies have examined deoxysotalol on its effects on prostaglandin (PGF2a and 15-methyl PGF2alpha)-evoked contraction using isolated rat uterus and also in potentiating the contractile effects of Oxytocin (O878500). /// References: Uloth, et al.: J. Med. Chem., 9, 88 (1966)| Narendranath, K.A., et al.: Euro. J. Pharmacol., 46, 15 (1977)| Gautam, C.S., et al., Indian. J. Med. Rsch., 76, 107 (1982)|