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Category: Amines, Chiral Reagents, Heterocycles, Metabolites and Impurities, Pharmaceuticals, Intermediates and Fine Chemicals, Sulfur and Selenium Compounds /// Application Notes: (E)-Cefpodoxime Proxetil (Cefpodoxime Proxetil EP Impurity D) is the (E)-isomer of Cefpodoxime Proxetil (C243860), an antibacterial and broad spectrum, orally absorbed third generation cephalosporin. The (E)-isomer tends to have less antibacterial activity than the (Z)-isomer. /// References: Fujimoto, K., et al.: J. Antibiot., 40, 370 (1987)| Utsui, Y., et al.: Antimicrob. Agents Chemother., 31, 1085 (1987)| Rajadurai, R., et al.: Anal. Chem.: Ind. J., 9, 265 (2010)