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Appearance: Dark Brown Solid /// Application Notes: 5(6)-Carboxyrhodamine 110 is a useful synthetic intermediate in the synthesis of 4,5-Disulfo Rhodamine-123 Carboxylic Acid Succinimidyl Ester Lithium Salt (D678830), a xanthene dye substituted two times by a sulfonic acid used as fluorescent probes, particularly in biological samples. It is more photostable than fluorescein. /// References: Stenman, U., et al.: Cancer Res., 51, 222 (1991)| Mitrunen, K., et al.: Clin. Chem., 41, 1115 (1995)| Karvinen, J., et al.: Anal. Biochem., 325, 317 (2004)| Hemmila, I., et al.: J. Fluoresc., 15, 529 (2005)