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Beschreibung

Appearance: Clear Colourless to Pale Yellow Oil /// Application Notes: Bromomethyl Methyl Ether acts as a reagent in the synthesis and evaluation of hydroxymethyl-aminocyclitols as glycosidase inhibitors, preparation of pyridine derivatives for minimizing CYP2C9 inhibition for cancer therapy. Also a reagent in the discovery of GBT 440, an orally bioavailable R state stabilizer of sickle cell Hb. /// References: Trapero, A., et al.: J. Org. Chem., 80, 3512 (2015)| Zak, M., et al.: J. Med. Chem., 59, 8345 (2016)| Metcalf, B.| et al.: ACS Med. Chem. Lett., 8, 321 (2017)