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Beschreibung

Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: A hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 and 42.93 µM, respectively. Recent studies suggest that it may have antiproliferative and anticancer properties. /// References: Girennavar, B. et al.: Bororg. Med. Chem., 14, 3684 (2007)| Girennavar, B. et al..: J. Food Sci., 72, C417 (2007)| Joa, H. et al.: J. Nat. Prod., 74, 1513 (2011)| Hirata, T. et al.: Bioorg. Med. Chem.