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Category: Aromatics, Chiral Reagents, Inhibitors, Metabolites and Impurities, Pharmaceuticals, Intermediates and Fine Chemicals, Pfizer compounds /// Application Notes: (3S,5R)-Atorvastatin Calcium Salt (Atorvastatin USP Related Compound B) is an isomeric impurity of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. /// References: Gupta, L. et al.: Spect. Acta. Mol. Biomol. Spect., 97, 495 (2012)| Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)